Vitamin C toxicity is a rare case as Vitamin c is water soluble, excess amount will be exceretd via kidneys. But stil there is a chance of vitamin c toxicity and death.
Anything in excess can kill you. for an example, water toxicity can kill a person. If you exceed the normal requirement of vitaqmin c, you are running a risk of vitamin c.
The upper limit for vitamin C intake is 2000 mg/day. Up to 10 g/day of vitamin C are sometimes taken for unproven health benefits, such as preventing or shortening the duration of viral infections or slowing or reversing the progression of cancer or atherosclerosis. Such doses may acidify the urine, cause nausea and diarrhea, interfere with the healthy antioxidant-prooxidant balance in the body, and, in patients with thalassemia or hemochromatosis, promote iron overload. Intake below the upper limit does not have toxic effects in healthy adults.
Clinical features of vitamin c toxicity are as follows:
Common side-effects vitamin c toxicity
1. Indigestions
2. Diarrhhoea
3. Nausea
4. Vomiting
5. Headache
6. Fatigue
7. Disturebed sleep
8. Skin rashes
Possible side-effects of vitamin toxicity
1. Iron poisoning as vitamin c enhances the absorption of iron.
2. Heamochromatosis
3. Heamolytic anemia can be precipitated if the patient is enzyme glucose-6-phosphate dehydrogenase (G6PD) deficient one.
4. Kidney stone
5. May precipitate abortions
Chance of overdose
As discussed previously, vitamin C exhibits remarkably low toxicity. The LD50 (the dose that will kill 50% of a population) in rats is generally accepted to be 11.9 grams per kilogram of body weight when taken orally. The LD50 in humans remains unknown, owing to medical ethics that preclude experiments which would put patients at risk of harm. However, as with all substances tested in this way, the LD50 is taken as a guide to its toxicity in humans and no data to contradict this has been found.
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