Alkaline phosphatase (ALP) enzyme test

Alkaline phosphatase (ALP) is an enzyme. Alkaline phosphatase (ALP) enzyme can be found in many tissues of the human body such as liver, bile duct, kidney, bone, and the placenta. This enzyme can also be found in several bacteria such as Escherichia coli. This enzyme is found in different forms, isoenzymes in human body. .

Alkaline phosphatase (ALP) enzyme test is useful to diagnose several diseases such as Cholestasis, cholecystitis, cholangitis, Paget's disease and osteosarcoma.

Normal Alkaline phosphatase (ALP) enzyme test is ranging from 20 to 140 IU/L.

High Alkaline phosphatase (ALP) enzyme test levels are found in following conditions;

1. liver diseases

• Cholestasis
• cholecystitis
• cholangitis
• cirrhosis
• hepatitis
• fatty liver
• liver tumor
• liver metastases

2. drug intoxication

• verapamil
• carbamazepine
• phenytoin
• erythromycin
• allopurinol
• ranitidine

3. Bone diseases

• Paget's disease
• osteosarcoma

4. other conditions

• prostatic cancer
• Fractured bone
• Multiple myeloma

Low Alkaline phosphatase (ALP) enzyme test levels are found in following conditions;

• Hypophosphatasia
• Postmenopausa
• Men with recent heart surgery
• malnutrition
• Pernicious anemia
• Chronic myelogenous leukemia